cresolPronunciation: /ˈkriːsɒl/Definition of cresol noun Chemistry each of three isomeric crystalline compounds present in coal-tar creosote, used as disinfectants. the ortho-, meta-, and para-methyl derivatives of phenol; chemical formula: CH3C6H4OH Origin: mid 19th century: from creosote + -olcresol in other Oxford dictionaries Definition of cresol in the US English dictionary