colonoscopePronunciation: /kəˈlɒnəskəʊp/Definition of colonoscope noun Medicine a flexible fibre-optic instrument inserted through the anus in order to examine the colon. Derivatives colonoscopyPronunciation: /kɒləˈnɒskəpi/ noun (plural colonoscopies)colonoscope in other Oxford dictionaries Definition of colonoscope in the US English dictionary