chylomicronPronunciation: /ˌkʌɪlə(ʊ)ˈmʌɪkrɒn/Definition of chylomicron noun Physiology a droplet of fat present in the blood or lymph after absorption from the small intestine. Origin: 1920s: from chylo- (combining form of chyle) + micronchylomicron in other Oxford dictionaries Definition of chylomicron in the US English dictionary