chuckwallaPronunciation: /ˈtʃʌkwɒlə/Definition of chuckwalla noun a large dark-bodied lizard, the male of which has a light yellow tail, native to the deserts of the south-western US and Mexico. Sauromalus obesus, family Iguanidae Origin: late 19th century: from Mexican Spanish chacahuala, from American Indianchuckwalla in other Oxford dictionaries Definition of chuckwalla in the US English dictionary