chlamydosporePronunciation: /ˈklamɪdə(ʊ)spɔː/Definition of chlamydospore noun Botany (in certain fungi) a thick-walled hyphal cell which functions like a spore. Origin: late 19th century: from Greek khlamus, khlamud- 'cloak' + sporechlamydospore in other Oxford dictionaries Definition of chlamydospore in the US English dictionary