cephalonPronunciation: /ˈsɛfəlɒn, ˈkɛf-/Definition of cephalon noun Zoology (in some arthropods, especially trilobites) the region of the head, composed of fused segments. Origin: late 19th century: from Greek kephalē 'head'cephalon in other Oxford dictionaries Definition of cephalon in the US English dictionary