asparaginePronunciation: /əˈsparədʒiːn/Definition of asparagine noun [mass noun] Biochemistry a hydrophilic amino acid which is a constituent of most proteins. An amide of aspartic acid; chemical formula: CONH2CH2CH(NH2)COOH Origin: early 19th century: from asparagus (which contains it) + -ine4asparagine in other Oxford dictionaries Definition of asparagine in the US English dictionary