arsphenaminePronunciation: /ɑːsˈfɛnəmiːn, -ɪn/Definition of arsphenamine noun [mass noun] Medicine a synthetic organic arsenic compound formerly used to treat syphilis and other diseases. See also Ehrlich, Paul.Origin: early 20th century: blend of arsenic, phenyl, and aminearsphenamine in other Oxford dictionaries Definition of arsphenamine in the US English dictionary