amoxycillinPronunciation: /əˌmɒksɪˈsɪlɪn/ (also amoxicillin)Definition of amoxycillin noun [mass noun] Medicine a semi-synthetic penicillin closely related to ampicillin and with similar properties, but more readily absorbed when taken orally. Origin: 1970s: from amino + oxy-2 + penicillinamoxycillin in other Oxford dictionaries Definition of amoxycillin in the US English dictionary