agranulocytosisPronunciation: /əˌgranjʊlə(ʊ)sʌɪˈtəʊsɪs/Definition of agranulocytosis noun [mass noun] Medicine a deficiency of granulocytes in the blood, causing increased vulnerability to infection. Origin: early 20th century: from a-1 + granulocyte + -osisagranulocytosis in other Oxford dictionaries Definition of agranulocytosis in the US English dictionary