acyclicPronunciation: /eɪˈsʌɪklɪk, -ˈsɪk-/Definition of acyclic adjective 1not displaying or forming part of a cycle. (of a woman) not having a menstrual cycle: donor age showed no influence on chance of pregnancy in acyclic patients 2 Chemistry (of a compound or molecule) containing no rings of atoms: simple acyclic alkenesacyclic in other Oxford dictionaries Definition of acyclic in the US English dictionary