acalculiaPronunciation: /ˌeɪkalˈkjuːlɪə/Definition of acalculia noun [mass noun] Medicine loss of the ability to perform simple calculations, typically resulting from disease or injury of the parietal lobe of the brain. Origin: early 20th century: from a-1 'not' + Latin calculare 'calculate' + -ia1acalculia in other Oxford dictionaries Definition of acalculia in the US English dictionary