UrukPronunciation: /ˈʊrʊk/Definition of Uruk an ancient city in southern Mesopotamia, to the north-west of Ur. One of the greatest cities of Sumer, it was built in the 5th millennium bc and is associated with the legendary hero Gilgamesh. Arabic name Warka; biblical name Erech.Uruk in other Oxford dictionaries Definition of Uruk in the US English dictionary