SeleucidPronunciation: /sɪˈluːsɪd/Definition of Seleucid adjective relating to or denoting a dynasty ruling over Syria and a great part of western Asia from 312 to 64 bc. Its capital was at Antioch. noun a member of the Seleucid dynasty. Origin:from Seleucus Nicator (the founder, one of Alexander the Great's generals) + -id3Seleucid in other Oxford dictionaries Definition of Seleucid in the US English dictionary