OtomiPronunciation: /ˌəʊtəˈmiː/Definition of Otomi noun (plural same) 1a member of an American Indian people inhabiting parts of central Mexico. 2 [mass noun] the Otomanguean language of the Otomi. adjective relating to the Otomi or their language. Origin:via American Spanish from Nahuatl otomih, literally 'unknown'Otomi in other Oxford dictionaries Definition of Otomi in the US English dictionary