OreoPronunciation: /ˈɔːrɪəʊ/Definition of Oreo noun (plural Oreos) US trademark a chocolate biscuit with a white cream filling. informal, derogatory a black American who is seen, especially by other black people, as wishing to be part of the white establishment. Origin: early 20th century: invented nameOreo in other Oxford dictionaries Definition of Oreo in the US English dictionary