MetisPronunciation: /meɪˈtiːs/Definition of Metis noun (plural same) (in Canada) a person of mixed race, especially one having white and American Indian parentage. adjective denoting or relating to people of mixed race in Canada. Origin:from French métis, from Latin mixtus 'mixed' (see also mestizo)Metis in other Oxford dictionaries Definition of Metis in the US English dictionary