LeónPronunciation: /leɪˈɒn/Definition of León 1a city in northern Spain; population 135,119 (2008). It is the capital of the province and former kingdom of León, now part of Castilla-León region. 2an industrial city in central Mexico; population 1,137,465 (2005). 3a city in western Nicaragua, the second-largest city in the country; population 174,051 (2006). León in other Oxford dictionaries Definition of León in the US English dictionary