Languedoc-RoussillonPronunciation: /ˌruːsɪˈjɒ̃, ʀusijɔ̃/Definition of Languedoc-Roussillon a region of southern France, on the Mediterranean coast, extending from the Rhône delta to the border with Spain. Languedoc-Roussillon in other Oxford dictionaries Definition of Languedoc-Roussillon in the US English dictionary