LabruscaPronunciation: /ləˈbrʊskə/Definition of Labrusca noun [mass noun] a variety of grape obtained from a wild vine native to the eastern US. Vitis labrusca, family Vitaceae a wine made from the Labrusca grape. Origin:from Latin labrusca, denoting a wild vineLabrusca in other Oxford dictionaries Definition of Labrusca in the US English dictionary