IroquoianPronunciation: /ɪrəˈkwɔɪən, -ˈkɔɪ-/Definition of Iroquoian noun [mass noun] a language family of eastern North America, including Cherokee and Mohawk. With the exception of Cherokee, all its members are extinct or nearly so. adjective relating to the Iroquois people or the Iroquoian language family. Iroquoian in other Oxford dictionaries Definition of Iroquoian in the US English dictionary