Gila monsterPronunciation: /ˈhiːlə/Definition of Gila monster noun a venomous beaded lizard native to the south-western US and Mexico. Heloderma suspectum, family Helodermatidae Origin: late 19th century: named after Gila, a river in New Mexico and ArizonaGila monster in other Oxford dictionaries Definition of Gila monster in the US English dictionary