Gethsemane, Garden ofPronunciation: /gɛθˈsɛməni/Definition of Gethsemane, Garden of a garden between Jerusalem and the Mount of Olives, where Jesus went with his disciples after the Last Supper and was betrayed (Matt. 26:36-46). Gethsemane, Garden of in other Oxford dictionaries Definition of Gethsemane, Garden of in the US English dictionary