FatimaPronunciation: /ˈfatɪmə/Definition of Fatima (circa 606–32 ad), youngest daughter of the prophet Muhammad and wife of the fourth caliph, Ali. The descendants of Muhammad trace their lineage through her; she is revered especially by Shiite Muslims as the mother of the imams Hasan and Husayn. Fatima in other Oxford dictionaries Definition of Fatima in the US English dictionary