F1Pronunciation: /ɛf/ (also f)Translate F | into French | into German | into Italian | into Spanish Definition of F noun (plural Fs or F's) 1the sixth letter of the alphabet. denoting the next after E in a set of items, categories, etc.. the sixth highest or lowest class of academic marks (also used to represent ‘Fail’): they are guaranteed F’s if they goof around (f) Chess denoting the sixth file from the left, as viewed from White’s side of the board. 2 (usually F) Music the fourth note of the diatonic scale of C major. a key based on a scale with F as its keynote. F in other Oxford dictionaries Definition of F in the US English dictionary