DenePronunciation: /ˈdɛneɪ, ˈdɛni/Definition of Dene noun (plural same) 1a member of a group of American Indian peoples of the Canadian North-West and Alaska. 2 [mass noun] any of the Athabaskan languages of the Dene. adjective relating to the Dene or their languages. Origin:from French Déné, from an Athabaskan word meaning 'people'Dene in other Oxford dictionaries Definition of Dene in the US English dictionary