Cowper's glandPronunciation: /ˈkaʊpəzɡland/Definition of Cowper's gland noun Anatomy either of a pair of small glands which open into the urethra at the base of the penis and secrete a constituent of seminal fluid. Origin: mid 18th century: named after William Cowper (1666–1709), English anatomistCowper's gland in other Oxford dictionaries Definition of Cowper's gland in the US English dictionary