CentaurusPronunciation: /sɛnˈtɔːrəs/ AstronomyDefinition of Centaurus a large southern constellation (the Centaur). It lies in the Milky Way and contains the stars Alpha and Proxima Centauri. (as genitive Centauri /sɛnˈtɔːri/) used with preceding letter or numeral to designate a star in this constellation:the star Lambda CentauriOrigin:LatinCentaurus in other Oxford dictionaries Definition of Centaurus in the US English dictionary