BirminghamDefinition of Birmingham 1 /ˈbəːmɪŋəm/ an industrial city in west central England; population 945,700 (est. 2009). 2 /ˈbəːmɪŋˌham/ an industrial city in north central Alabama; population 228,798 (est. 2008). Birmingham in other Oxford dictionaries Definition of Birmingham in the US English dictionary