-lysisPronunciation: /lɪsɪs/Definition of -lysis combining form denoting disintegration or decomposition: in nouns specifying an agent:hydrolysis in nouns specifying a reactant:haemolysis in nouns specifying the nature of the process:autolysisOrigin:via Latin from Greek lusis 'loosening'-lysis in other Oxford dictionaries Definition of -lysis in the US English dictionary