antagonist
Pronunciation: /anˈtag(ə)nɪst/
noun
- 1a person who actively opposes or is hostile to someone or something; an adversary: the woman was forcing her antagonist’s face into the mud
- 2 Biochemistry a substance which interferes with or inhibits the physiological action of another: LSD is a serotonin antagonistCompare with agonist.

Origin:
late 16th century: from French antagoniste or late Latin antagonista, from Greek antagōnistēs, from antagōnizesthai 'struggle against' (see antagonize)