tryptamine Syllabification: (tryp·ta·mine)Pronunciation: /ˈtriptəˌmēn/Definition of tryptamine noun Biochemistry a compound, of which serotonin is a derivative, produced from tryptophan by decarboxylation. A heterocyclic amine; chemical formula: C8H6NCH2CH2NH tryptamine in other Oxford dictionaries Definition of tryptamine in the British & World English dictionary