trypanosomiasis Syllabification: (try·pan·o·so·mi·a·sis)Pronunciation: /trəˌpanəsōˈmīəsis, ˈtripənə-/Definition of trypanosomiasis noun Medicine any tropical disease caused by trypanosomes and typically transmitted by biting insects, especially sleeping sickness and Chagas' disease. trypanosomiasis in other Oxford dictionaries Definition of trypanosomiasis in the British & World English dictionary