thymoma Syllabification: (thy·mo·ma)Pronunciation: /THīˈmōmə/Definition of thymoma noun (plural thymomas or thymomata /-mətə/) Medicine a rare, usually benign tumor arising from thymus tissue and sometimes associated with myasthenia gravis. Origin: early 20th century: from thymus + -omathymoma in other Oxford dictionaries Definition of thymoma in the British & World English dictionary