thiosulfate Syllabification: (thi·o·sul·fate)Pronunciation: /ˌTHī-ōˈsəlˌfāt/Definition of thiosulfate noun Chemistry a salt containing the anion S2O32, i.e., a sulfate with one oxygen atom replaced by sulfur. thiosulfate in other Oxford dictionaries Definition of thiosulfate in the British & World English dictionary