telomere Syllabification: (tel·o·mere)Pronunciation: /ˈtēləˌmi(ə)r, ˈtelə-/Definition of telomere noun Genetics a compound structure at the end of a chromosome. Derivatives telomericPronunciation: /ˌtēləˈmerik, ˌtelə-/ adjective Origin: 1940s: from Greek telos 'end' + meros 'part'telomere in other Oxford dictionaries Definition of telomere in the British & World English dictionary