supercoil Syllabification: (su·per·coil)Pronunciation: /ˈso͞opərˌkoil/ BiochemistryDefinition of supercoil noun another term for superhelix. verb [with object] form (a substance) into a superhelix: (as adjective supercoiled)a supercoiled circular DNA moleculesupercoil in other Oxford dictionaries Definition of supercoil in the British & World English dictionary