subprime Syllabification: (sub·prime)Pronunciation: /səbˈprīm/Translate subprime | into German | into Italian Definition of subprime adjective referring to credit or loan arrangements for borrowers with a poor credit history, typically having unfavorable conditions such as high interest rates:a coalition of subprime lenderssubprime in other Oxford dictionaries Definition of subprime in the British & World English dictionary