stilbestrol Syllabification: (stil·bes·trol)Pronunciation: /stilˈbesˌtrôl, -ˌträl/ (British stilboestrol)Definition of stilbestrol noun Biochemistry a powerful synthetic estrogen used in hormone therapy, as a postcoital contraceptive, and as a growth-promoting agent for livestock. Origin: 1930s: from stilbene + estrus + -olstilbestrol in other Oxford dictionaries Definition of stilbestrol in the British & World English dictionary