scleroprotein Syllabification: (scle·ro·pro·tein)Pronunciation: /ˌskli(ə)rōˈprōtē(ə)n/Definition of scleroprotein noun Biochemistry an insoluble structural protein such as keratin, collagen, or elastin. scleroprotein in other Oxford dictionaries Definition of scleroprotein in the British & World English dictionary