psychosurgery Syllabification: (psy·cho·sur·ger·y)Pronunciation: /ˌsīkōˈsərjərē/Definition of psychosurgery noun brain surgery, such as lobotomy, used to treat mental disorder. Derivatives psychosurgicalPronunciation: /-ˈsərjikəl/ adjective psychosurgery in other Oxford dictionaries Definition of psychosurgery in the British & World English dictionary