psychoneuroimmunology Syllabification: (psy·cho·neu·ro·im·mu·nol·o·gy)Pronunciation: /ˌsīkōˌn(y)o͝orōˌimyəˈnäləjē/Definition of psychoneuroimmunology noun Medicine the study of the effect of the mind on health and resistance to disease. psychoneuroimmunology in other Oxford dictionaries Definition of psychoneuroimmunology in the British & World English dictionary