prehypertension Syllabification: (pre·hy·per·ten·sion)Pronunciation: /ˌprēˌhīpərˈtenSHən/Definition of prehypertension noun the condition of having blood pressure between 120/80 mmHg and 139/89 mmHg, considered an indication of risk for hypertension. Derivatives prehypertensivePronunciation: /-siv/ adjective Origin: early 21st century