osmoregulation Syllabification: (os·mo·reg·u·la·tion)Pronunciation: /ˌäzmōˌregyəˈlāSHən/Definition of osmoregulation noun Biology the maintenance of constant osmotic pressure in the fluids of an organism by the control of water and salt concentrations. Derivatives osmoregulatoryPronunciation: /-ˈregyələˌtôrē/ adjective osmoregulation in other Oxford dictionaries Definition of osmoregulation in the British & World English dictionary