orthognathous Syllabification: (or·thog·na·thous)Pronunciation: /ôrˈTHägnəTHəs/Definition of orthognathous adjective Anatomy (especially of a person) having a jaw that does not project or recede, so that the facial profile is nearly vertical. Origin: mid 19th century: from ortho- 'straight' + Greek gnathos 'jaw' + -ousorthognathous in other Oxford dictionaries Definition of orthognathous in the British & World English dictionary