omega Syllabification: (o·me·ga)Pronunciation: /ōˈmāgə, ōˈmē-/Definition of omega noun the twenty-fourth, and last, letter of the Greek alphabet (Ω, ω), transliterated as ‘o’ or ‘ō.’. the last of a series; the final development: [as modifier]:the omega point (Omega) [followed by Latin genitive] Astronomy the twenty-fourth star in a constellation:Omega Scorpii symbol (Ω) ohm(s):a 100Ω resistorOrigin:from Greek ō mega 'big O'omega in other Oxford dictionaries Definition of omega in the British & World English dictionary