mucus Syllabification: (mu·cus)Pronunciation: /ˈmyo͞okəs/Translate mucus | into German | into Italian | into Spanish Definition of mucus noun a slimy substance, typically not miscible with water, secreted by mucous membranes and glands for lubrication, protection, etc.. a gummy substance found in plants; mucilage. Origin: mid 17th century: from Latinmucus in other Oxford dictionaries Definition of mucus in the British & World English dictionary