meperidine Syllabification: (me·per·i·dine)Pronunciation: /məˈperəˌdēn, -ˌdin/Definition of meperidine noun Medicine a synthetic compound used as a painkilling drug, especially for women in labor. Origin: 1940s: blend of methyl and piperidinemeperidine in other Oxford dictionaries Definition of meperidine in the British & World English dictionary