medicinal leech Syllabification: (me·dic·i·nal leech)Definition of medicinal leech noun a large European leech, introduced to North America, used in medicine for bloodletting. After biting, it secretes an anticoagulant to ensure the flow of blood. Hirudo medicinalis, family Hirudidae medicinal leech in other Oxford dictionaries Definition of medicinal leech in the British & World English dictionary