medication Syllabification: (med·i·ca·tion)Pronunciation: /ˌmedəˈkāSHən/Translate medication | into French | into German | into Italian | into Spanish Definition of medication noun a substance used for medical treatment, especially a medicine or drug:he’d been taking medication for depression certain medications can cause dizziness treatment using drugs:chronic gastrointestinal symptoms which may require prolonged medicationmedication in other Oxford dictionaries Definition of medication in the British & World English dictionary